While these symptoms are reported, the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) does not include them on the recognized list of symptoms. It is still unclear whether these symptoms are directly caused by the disorder. People living with post-traumatic stress disorder (PTSD) experience flashbacks of stressful, even painful situations. Type 1 HPPD is typically experienced as brief, random “flashbacks.” On the other hand, type 2 HPPD is generally long term, disturbing, and pervasive.

Medical tools and resources
It is crucial to approach these substances with caution and respect, ensuring proper research, responsible use, and guidance from trained professionals when exploring their potential. HPPD is a condition that is often underdiagnosed or just not taken seriously. Up to one-third of people using psychedelics may report some kind of lasting change in their visual experiences, but only a subset of these find them to be seriously distressing. The risk may be small, but the treatments are highly inadequate, so it is worth exercising some caution in terms of mitigating risks before taking any drugs. We do not encourage drug use, but for harm reduction purposes it may be more advisable to use plant-based versions (e.g. magic mushrooms) to avoid contamination with harmful synthetic substances. If you think you might have HPPD, we encourage you to seek help from a medical professional and seek support from online communities.
Physical and neurological exams may be conducted to rule out other conditions. Additionally, psychological assessments and possibly imaging tests may be recommended. It’s important to be open and honest with your healthcare provider to receive an accurate diagnosis and appropriate treatment. Importantly, other etiologies of this distress such as post-traumatic stress disorder, depersonalization, derealization, etc. must be excluded.
This could mean hallucinogens may trigger longer-term brain changes. HPPD refers to when someone reexperiences visual and emotional sensations that can surface with psychedelic use after a substance is out of your system. The kind of hallucinogen used as well as how much and whether they are taken with other substances can affect whether a person experiences HPPD and for how long they experience it. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care.
Empowering Recovery: Navigating Hallucinogen Persisting Perception Disorder (HPPD) with Dr. Steven Locke
Additionally, Dr. Locke has developed a what is Oxford House screening questionnaire for HPPD in collaboration with researchers at Johns Hopkins University. This tool can help you assess whether your symptoms align with HPPD and serve as a valuable resource to bring to any appointments with your healthcare provider. As an expert in HPPD, Dr. Locke understands the value of collaboration with other healthcare providers.
- All OCT findings fell within normal ranges (results available as a Appendix A1).
- Although HPPD is relatively uncommon, determining its prevalence is challenging, as many individuals may not seek medical help for their symptoms.
- The condition is most frequently reported among young adults who use hallucinogens recreationally, though it can affect individuals of any age.
Differential Diagnosis
While HPPD is recognized by some professionals, many psychiatrists and neurologists may not be fully familiar with the latest research or treatment options. Dr. Locke stays up-to-date with the most current clinical guidelines and offers a tailored approach to care based on each patient’s unique situation. Although there’s no cure for the condition, treatment for HPPD can reduce symptoms and help people with the disorder lead fuller lives.
What Is Hallucinogen-Persisting Perception Disorder (HPPD)?

The visual symptoms of HPPD are often accompanied—or made worse—by anxiety, depersonalization, or derealization. These are not core symptoms of HPPD, but they are common secondary effects caused by the stress and confusion the condition brings. These visual symptoms are not due to ongoing substance use, a psychotic disorder, or a neurological disease.
Dr.Oracle assumes no liability for clinical decisions based on this content. Because HPPD is relatively under-reported and under-researched, we still don’t know a huge deal about HPPD. A doctor can help provide advice on managing HPPD symptoms and may prescribe a course of drug therapy to help. If a doctor is not sympathetic to a person’s symptoms or does not want to explore HPPD as a diagnosis, then it is a good idea to speak to a different doctor.
- If symptoms are primarily visual and not tied to mood, HPPD is the more probable diagnosis.
- The only effect of the flashback you’ll experience is the visual disruption.
A Journey Through A Clinical Lesson at the Salpêtrière
Tolerance occurs when someone uses the same dose of https://storeromas.com/how-does-an-outpatient-alcohol-detox-work-2/ a drug regularly, and over time, the drug’s effects decrease. With HPPD, the theory is that using the same dose of hallucinogens regularly increases the effects rather than decreases them. Many people develop treatment plans to manage the symptoms and live well-balanced lives.

Some people experience these visual disturbances only once after using hallucinogenic drugs. For others, the disturbances may occur frequently but not be very bothersome. This may have biased the frequency of visual snow as patients with HPPD experiencing this symptom were more likely to be referred. Patient numbers for both our cases and literature reports were small.
Non-Psychedelic or Psychoactive Drugs and HPPD
It’s often compared to the static you might see on an untuned television screen. Pilecki, B., Luoma, J. B., Bathje, G. J., Rhea, J., & Narloch, V. F. Ethical and legal issues in psychedelic harm reduction and integration therapy. The causes of HPPD2 are similar to HPPD1, with hallucinogen use being a primary factor. However, the chronic nature suggests a more profound alteration in brain function, possibly affecting neurotransmitter systems or neural pathways hppd meaning more deeply.
